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This technique is used in cases in which at least one fallopian tube is normal. The eggs and the sperm are deposited in the fallopian tube, and therefore, the normal physiological fertilization process is mimicked. The whole procedure is performed under general anaesthetics. The preparation is similar to In Vitro Fertilization, except for egg collection being performed by laparoscopy.
This technique may be recommended in some patients as a first option in order to enable the sperm to fertilize the eggs. If at least one fallopian tube is normal and fertilization has occurred in vitro, the fertilized eggs can be transferred to the fallopian tube under general anaesthetics. The only difference between GIFT and ZIFT is that with GIFT fertilizations occurs in the fallopian tube and with ZIFT fertilization occurs in the laboratory and the embryo is then transferred to the fallopian tube.