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While having a healthy baby is desirable for any family, "Gender Selection" has also attracted great interest and controversy over the years. A few of the reasons why couples may wish to request a specific gender, is the desire to balance the gender among members of a family; to avoid genetic disorders that are more common in one sex (sex linked disorders); or sometimes, to accommodate cultural or social norms. These factors may encourage families to choose traditional or new treatments for gender selection. In the absence of a boy or girl in the family, many couples face multiple cultural issues and may try to have the gender that they wished for all their lives. There are different types of procedures used for sex selection, most of which involve separating X and Y chromosomes from sperm or involve the selection of embryos with male or female DNA in order to produce a baby of the desired gender.
The method of choice for sex selection in our center is preimplantation genetic diagnosis (PGD), using FISH or PCR techniques. This is a reliable and accurate method for selecting the desirable gender with 95% success rate. As with all ICSI procedures, eggs are removed after ovarian stimulation and fertilized in a laboratory using microinjection method. To make use of PGD the couple has to go through routine IVF procedure so that several embryos can be tested when they are just three days old. After fertilization, the embryo will grow to eight cells. Typically, one to two cells are removed by biopsy and are tested by FISH or PCR techniques, determining embryo's gender. Finally the embryos with the desirable gender by the couple will be transferred into a woman's uterus.
For this technique developed by R. Ericsson, the sperm is filtered through a salt albumin solution in small test tubes. At the final incubation, the bottom layer of the filtration is collected and processed and then an intrauterine insemination (IUI) is done with this sample. This method has been in use since the mid-1970s and is based on the assumption that Y-sperm swim faster than X-sperm. Dr. Ericsson’s published success rates using this method demonstrate approximately a 70% chance of conceiving with the desirable gender when pregnancy occurs.
PLAN YOUR VISIT FOR GENDER SELECTION